- E-mail : info@cixmechpharma.com
Candesartan is an angiotensin II receptor antagonist. Candesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Candesartan is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.Candesartan is also used to treat kidney problems caused by type 2 diabetes.
|
ITEMS |
SPECIFICATIONS |
RESULTS |
|
Description |
White or almost white crystalline powder |
Almost white crystalline powder |
|
Solubility |
Freely soluble in Chloroform Sparingly soluble in anhydrous ethanol Slightly soluble in acetonitrile Practically insoluble in water |
Conforms |
|
HPLC UV IR |
Must conform to reference standard Must conform to reference standard Must conform to reference standard |
Conforms Conforms Conforms |
|
Loss on drying |
Not more than 0.5% |
0.06% |
|
Chloride |
Not more than 0.035% |
<0.035% |
|
Residue on ignition |
Not more than 0.1% |
0.03% |
|
Heavy metals |
Not more than 10 ppm |
<10 ppm |
|
Ethyl candesartan Desethyl candesartan Other Individual impurity Total impurities |
Not more than 0.3% Not more than 0.3% Not more than 0.1% Not more than 1.0% |
0.11% 0.15% 0.05% 0.37% |
|
Ethanol Acetone Ethyl acetate Dichloromethane N, N-Dimethylformamide n-Heptane Acetic acid |
Not more than 0.5% Not more than 0.5% Not more than 0.5% Not more than 0.06% Not more than 0.088% Not more than 0.5% Not more than 0.3% |
Conforms 0.004% Conforms Conforms Conforms Conforms Conforms |
|
Assay |
98.0~102.0% |
98.65% |
Packaging details:
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Packaging details: |
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
|
Storage: |
Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
|
Shelf Life: |
5 years if sealed and store away from direct sun light. |
